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Colchicine - Overview
Colchicine, marketed under the brand names Colcrys and Mitigare, is a medication primarily used for the treatment and prevention of gout flares. People who need a colchicine prescription can connect with a provider through Push Health who can prescribe colchicine when appropriate to do so.
Colchicine - Mechanism of Action
What is colchicine and how does colchicine work? Colchicine is a type of alkaloid medication used in managing gout flares. It is not entirely clear how colchicine exerts its effect although it may interfere with processes that lead to the activation of inflammatory markers known as interleukins. Colchicine may also interfere with neutrophil movement and activation as it pertains to producing symptoms of gout. When used for gout prophylaxis, the starting dose of colchicine is frequently colchicine 0.6 mg daily. The colchicine dose for gout prophylaxis can be titrated up at the discretion of the medical provider but usually should not exceed 1.2 mg daily. Colchicine sometimes used in conjunction with allopurinol, indomethacin and probenecid as part of a gout treatment plan. Colchicine is also used in treating some patients with Familial Mediterranean fever. Colchicine is should not otherwise be considered an analgesic medication.
Colchicine - Dosage and Price
Colchicine is an oral medication that can be taken without regard to meals. After being administered orally, colchicine is absorbed well, reaching peak concentrations in the plasma in under 3 hours in healthy adults with an elimination half-life of roughly 30 hours. Colchicine is largely excreted in the urine. Colchicine is available as colchicine 0.6 mg tablets. Colchicine itself is a pale yellow powder that dissolve in water. Colchicine tablets are moderately expensive, with a price of colchicine 0.6 mg tablets at just over $2 per tablet. Colchicine coupons may be available online to help cover the cost of the medication and some insurance plans may also cover any costs associated with colchicine tablets. Colchicine 0.6 mg tablets are purple, film-coated tablets shaped like a capsule and scored on one side. Colchicine tablets should be stored at 20° C to 25° C.
Can I Buy Colchicine Online?
Colchicine is a prescription medication in the United States. Colchicine OTC (over the counter) is not available at pharmacies and one cannot just buy colchicine online. People who need a colchicine prescription can use Push Health to connect with a medical provider who can prescribe colchicine when appropriate to do so, making the process of getting colchicine when medically necessary a little simpler.
Colchicine - Side Effects
Colchicine can cause a variety of side effects when used, including diarrhea, throat pain, nausea, vomiting, and abdominal pain. Colchicine can cause blood dyscrasias and can interact with other medications. Muscle disorders such as rhabdomyolysis have been reported in association with colchicine use. Colchicine and alcohol should not be used at the same time. Questions about side effects related to colchicine use should be discussed with one's medical provider and pharmacist.
More Colchicine Information
Last updated February 3, 2021. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions.