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Linzess (Linaclotide) - Overview

Linaclotide, marketed under the name Linzess, is a medication used in adults in the treatment of irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation. People who might need a Linzess prescription can connect with a medical provider through Push Health who can prescribe Linzess if appropriate and safe to do so.

How Does Linzess Work?

What is Linzess used for? Linzess (linaclotide) belongs to a class of medications known as guanylate cyclase-C agonists and is a 14-amino acid peptide. Linzess is used in the management of constipation in adults with chronic idiopathic constipation and irritable bowel syndrome with constipation - somewhat similar to dicyclomine. Linaclotide, along with some of its metabolites, bind to the surface of the intestines, resulting in metabolic changes which increase the secretion of chloride and bicarbonate into the intestinal lumen. Through these secretions, linaclotide is thought to increase transit of fluids in the intestines and reduce pain. Following administration, the systemic availability of Linzess is low and plasma concentrations of linaclotide are not measurable. Some linaclotide is excreted in the stool.

Linzess - Dosage and Coupons

Linzess capsules are linaclotide-coated beads in hard gelatin in addition to some inactive ingredients. Linzess capsules are orally administered and come in Linzess 145 mcg and Linzess 290 mcg capsules. Linzess 145 mcg capsules and Linzess 290 mcg capsules are white to off-white opaque hard gelatin capsules. Linaclotide itself is found as a white to off-white powder that is slightly soluble in water. Linzess is expensive, costing approximately $15 per Linzess 145 mcg capsule when one is paying out of pocket for the medication. Linzess coupons may be available at times online or from the manufacturer. Linzess capsules should be stored at 25° C.

Can I Buy Linzess Online?

Linzess is a prescription medication in the US. For this reason, one cannot simply buy Linzess online or get Linzess OTC (over the counter) from a pharmacy without first consulting a licensed medical provider and obtaining a prescription. However, people who might need a Linzess medication prescription can connect with a licensed medical provider through Push Health who can prescribe Linzess capsules if appropriate to do so.

Linzess - Side Effects

Linzess can cause side effects when used. Side effects of Linzess (linaclotide) use include diarrhea, flatulence, abdominal pain and abdominal distension. Linzess can also cause gastroesophageal reflux disease, fatigue and vomiting. Linzess and alcohol use should be avoided. People with a known hypersensitivity to Linzess or ingredients in the formulation should not use the medication. It is recommended that anyone planning to use Linzess or linaclotide discuss possible side effects and other concerns with their pharmacist and medical provider before using the medication.

More Linzess Information

Last updated August 20, 2020. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions.