Qlosi Prescription Online
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Qlosi - Overview
Qlosi is a prescription eye drop medication that is FDA-approved to improve near vision in adults with presbyopia (age-related farsightedness). People who might need a Qlosi prescription can use Push Health to connect with a medical provider who can prescribe Qlosi medication when appropriate to do so.
What Is Qlosi Used For?
Qlosi prescription medication contains the active ingredient pilocarpine 0.4%. Qlosi medication is sometimes prescribed to people who need treatment for presbyopia (age-related farsightedness) - an age-related condition in which the eye's crystalline lens gradually loses the flexibility needed to focus on near objects. Presbyopia typically begins around age 45 as the eye's lens loses flexibility.
Qlosi is a muscarinic agonist that works by contracting the iris sphincter muscle, reducing pupil size while preserving some light responsiveness. This temporarily improves near and intermediate vision for many patients who would otherwise need reading glasses. Qlosi is one of three prescription presbyopia eye drops currently available in the United States, alongside Vuity (pilocarpine 1.25%) and Vizz (aceclidine 1.44%).
Qlosi vs. Vuity and Vizz - How Do They Compare?
Qlosi, Vuity, and Vizz are all FDA-approved prescription eye drops for presbyopia, but they differ in active ingredient, dose, mechanism, and side effect profile.
Qlosi vs. Vuity. Both Qlosi and Vuity contain pilocarpine, but at different concentrations. Vuity uses the higher 1.25% pilocarpine concentration and produces stronger pupil constriction but potentially more myopic shift (distance blur) in some patients. Qlosi uses the lower 0.4% concentration with the intention of providing effective near vision improvement with a reduced tendency to blur distance vision. Patients who tried Vuity and experienced significant distance blur may find Qlosi's lower-dose formulation better tolerated.
Qlosi vs. Vizz. Vizz (aceclidine 1.44%) uses a different active ingredient entirely - aceclidine rather than pilocarpine. Aceclidine is a predominantly pupil-selective muscarinic agonist that contracts the iris sphincter with minimal stimulation of the ciliary muscle and produces near vision improvement with very little myopic shift. Vizz is also once-daily and lasts up to 10 hours. Patients who want to minimize distance blur may prefer Vizz over either pilocarpine-based option.
Qlosi - Dosage and Cost
Qlosi is typically administered as one drop in each eye once daily. An optional second drop is sometimes used 2-3 hours after the first dose for extended near vision benefit (up to 8 hours for some patients). Onset is usually within 15-30 minutes. Remove contact lenses before instilling drops and follow your provider's guidance on when to reinsert them.
Qlosi is a branded prescription medication and out-of-pocket pricing varies by pharmacy. Prices generally range from $80-100 per carton (30 vials). Insurance coverage varies and may require prior authorization. Prescription savings cards or programs may also help with medication costs.
Can I Buy Qlosi Online?
Qlosi requires a prescription and is not available over the counter. Through Push Health, people who might need Qlosi can use Push Health to connect with a medical provider who can prescribe Qlosi medication when appropriate to do so.
Qlosi - Frequently Asked Questions
What is Qlosi used for?
Qlosi is an FDA-approved prescription eye drop for the treatment of presbyopia - the age-related loss of near-focusing ability that typically begins around age 45.
Is Qlosi the same as Vuity?
Both Qlosi and Vuity contain pilocarpine, but Qlosi uses a lower concentration (0.4% vs 1.25%). The lower dose is intended to provide near vision improvement with less myopic shift (distance blur).
How does Qlosi compare to Vizz?
Vizz uses aceclidine 1.44%, a more pupil-selective agent that generally causes less distance blur and may last longer. Qlosi is a lower-dose pilocarpine option for patients who prefer that approach.
Does Qlosi cause blurry distance vision?
Qlosi can cause some transient blurring of distance vision or difficulty in dim light, especially right after use. The 0.4% strength is designed to reduce this effect relative to higher dose pilocarpine but individual results may vary.
How quickly does Qlosi work and how long does it last?
Qlosi typically begins working within 15-30 minutes. Near-vision benefits can last 6-8 hours. A second drop may extend the effect.
Can I use Qlosi with contact lenses?
Remove contacts before using Qlosi drops. Discuss further use of contact lenses with your medical provider.
Can I get a Qlosi prescription online?
Yes. Through Push Health, people who need a Qlosi prescription can connect with a licensed medical provider who can evaluate their presbyopia symptoms and prescribe Qlosi eye drops when appropriate — without an office visit. Prescriptions are sent electronically to a pharmacy of the patient's choice.
Qlosi - Side Effects
Qlosi prescription medication can cause side effects when used. The most common side effect is transient blurry vision immediately after instilling the drop, potentially affecting distance vision and limiting activities such as driving while the drop is active. Headache and eye redness or irritation have also been reported. These side effects are generally mild and relate to pilocarpine's pupil-constricting mechanism. Patients with a history of retinal detachment, narrow-angle glaucoma, or other conditions that may be exacerbated by pupil constriction should discuss these conditions with their medical provider before using Qlosi eye drops. Patients with a known hypersensitivity to pilocarpine or any component of the Qlosi formulation should not use this medication. Alcohol does not have a documented pharmacokinetic interaction with pilocarpine eye drops but patients should discuss alcohol use and any other health concerns with their medical provider prior to starting Qlosi medication.
How to Get a Qlosi Prescription with Push Health
- Complete a brief health intake. Describe your vision difficulties, current use of reading glasses or contacts, and any relevant eye health history (e.g. retinal issues, glaucoma, iritis, surgeries).
- Connect with a licensed medical provider. A provider will review your information and evaluate whether Qlosi or an alternative might be appropriate. Same-day consultations are available.
- Receive your prescription electronically. If Qlosi is appropriate, your provider will send a prescription to a pharmacy of your choice - no office visit required.
- Begin treatment. One drop in each eye once daily. Follow your prescription as written and discuss improvements and side effects with your medical provider.
No health insurance or subscription is required. Medical providers are available now.
More Qlosi Information
Last updated August 17, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.