Retatrutide Drug Information

Retatrutide - Overview

Retatrutide medication is a drug that is under investigated for weight loss. Retatrutide medication is not approved by the FDA and is not available in the US market at this time.

What Is Retatrutide Used For?

Retatrutide medication, sometimes referred to as LY3437943, is an investigational drug. Retatrutide medication belongs to a new class of medications that combine glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 (GLP-1) and glucagon. Data from one pre-clinical study also suggests that retatrutide medication might reduce cancer progression. Other studies are looking at how retatrutide medication might impact cardiovascular outcomes in patients with type 2 diabetes as well as metabolic dysfunction-associated steatotic liver disease.

Retatrutide - Dosage and Cost

Retatrutide medication demonstrates pharmacokinetics which are dose proportional. With a mean half-life of approximately 6 days, retatrutide prescription medication will likely be suitable for weekly dosing. Dosage and cost information for the retatrutide prescription drug candidate is not available at this time.

Retatrutide And Weight Loss

Retatrutide medication, similar to orforglipron, is under investigation for use in weight loss. In one phase 2 trial, retatrutide treatment for 48 weeks resulted in substantial reductions in body weight. Another study also found that once-weekly retatrutide medication use was associated with a significant reduction in body weight. Retatrutide will likely be a once-weekly injection and is similar to drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). Retatrutide targets GLP-1 receptors and two other hormones known as glucagon and glucose-dependent insulinotropic polypeptide (GIP). Due to these actions, retatrutide is sometimes referred to as a "triple G" (GGG) or tri-agonist drug.

Can I Buy Retatrutide Online?

Retatrutide prescription medication is not approved in the United States and, as such is not available at this time. It is not recommended that anyone try to buy retatrutide online, either.

Retatrutide - Side Effects

Retatrutide medication can cause side effects when used but, to date, is generally well tolerated and comparable to control groups. Retatrutide may cause adverse reactions such as an increased heart rate and tingling of the skin with the most common side effect generally reported as being gastrointestinal.

More Retatrutide Information

• Retatrutide - NEJM